AbLang-2
OPIG (Oxford)
Antibody-specific language model for sequence restoration, per-residue scoring, and embedding. Reduces germline bias from original AbLang.
Best For
Humanization scoring; mutation tolerance assessment; sequence restoration
License
Open Source (check repo)
Strengths
- +Antibody-specific training
- +Paired VH/VL support
- +Reduced germline bias
Limitations
- −Sequence-only (no structural context)
- −Does not generate novel CDRs
R&D Pipeline Coverage
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