Novo Nordisk
Enterprise-wide AI integration across drug discovery, manufacturing, and commercial ops. Full integration planned by end of 2026. OpenAI will also train Novo's global workforce.
Deal Intelligence
Track the biggest biotech deals — M&A, venture rounds, licensing, partnerships, and IPOs shaping the industry.
Total Deals
19
Q1 2026 Value
$9.3B
Avg VC Round
$191M
Top Modality
AI Platform
19 deals
Enterprise-wide AI integration across drug discovery, manufacturing, and commercial ops. Full integration planned by end of 2026. OpenAI will also train Novo's global workforce.
Oversubscribed Series A for extrahepatic RNA therapeutics. Platform delivers RNA drugs beyond liver targets — a key limitation of current generation ASOs and siRNAs.
Gilead acquires Munich-based ADC specialist Tubulis for $3.15B upfront + $1.85B milestones. Tubulis will operate as a dedicated ADC R&D unit within Gilead's oncology division.
Major funding round for the longevity-focused biotech advancing small molecule programs targeting age-related diseases.
Largest AI drug discovery deal to date. Lilly gains exclusive global rights to develop and commercialize preclinical assets discovered using Insilico's Chemistry42 and PandaOmics platforms.
Novartis pays up to $2B for Excellergy's Exl-111, a half-life extended anti-IgE antibody in Phase 1 targeting allergy — positioned as a next-gen Xolair successor.
ADC co-development deal for endometrial cancer. Mid-stage trial showed 'clinically meaningful' efficacy. BioNTech expanding beyond mRNA into ADC modality.
Series A launch. Developing anti-PACAP monoclonal antibody SLTE-1009 (licensed from China's DartsBio) for migraine prevention. Phase 1 planned mid-2026.
Follow-on public offering after Merck's $28-32B acquisition talks collapsed in Jan 2026. Revolution continues developing its RAS(ON) inhibitor platform independently for KRAS-mutant cancers.
Lilly acquires Orna for up to $2.4B to enter in vivo CAR-T. Orna's circular RNA platform engineers immune cells directly inside the body, eliminating the need for cell extraction.
AI-powered drug development collaboration for novel cardiometabolic therapies. Qilu has used Insilico's PandaOmics since 2021; deal deepens the AI platform integration.
AstraZeneca acquires AI-driven oncology startup MediMab, adding computational antibody design capabilities to its biologics pipeline.
Lilly secures multi-year access to Chai Discovery's protein structure and biologics design foundation models. Mid-eight-figure annual fee. First-in-class medicines expected in clinical trials by end of 2027.
GSK commits $50M upfront to Noetik for AI-driven cancer clinical outcome prediction. Part of a Q1 2026 wave of pharma-AI platform deals alongside Lilly–Chai and Pfizer–Boltz.
Pfizer partners with Boltz for AI-powered small molecule drug discovery, implementing Boltz's structure prediction platform across Pfizer's R&D pipeline.
Expanded partnership deploying ChatGPT Enterprise across Moderna's business for mRNA vaccine target identification and process optimisation.
First biotech IPO of 2026. Upsized offering of 17.65M shares at $18/share. Lead program Ac-AKY-1189 is a miniprotein radiopharmaceutical targeting Nectin-4 expressing tumors.
Novartis acquires Avidity for ~$12B ($72/share), gaining three late-stage RNA programs for neuromuscular diseases. Completed Feb 2026. Largest RNA therapeutics deal ever.
One of the largest biotech acquisitions of late 2025. Metsera went public earlier in the year and was acquired for ~$10B, validating the obesity/metabolism thesis.