PrimeKG
Zitnik Lab, Harvard Medical School
Precision Medicine Knowledge Graph integrating 20 sources across 10 biological scales. 17,080 diseases with 4M+ relationships including drug indication and off-label use edges.
Best For
ML-based drug repurposing with GNNs; disease module analysis; drug synergy studies
License
Open Source (check repo)
Strengths
- +10 biological scales
- +Drug indication + off-label edges
- +Designed for ML
Limitations
- −Static snapshot (2022-2023)
- −Smaller disease coverage than newer graphs
R&D Pipeline Coverage
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