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Peptide Therapeutics

Short chains of amino acids that can modulate biological targets with high specificity. The GLP-1 receptor agonist revolution (semaglutide, tirzepatide) has made peptides the fastest-growing therapeutic modality by revenue.

Key Companies

Novo NordiskEli LillyZealand PharmaProtagonist Therapeutics

Recent Signals

DEALS & FUNDING

Kailera Therapeutics Files for $533M IPO, Largest Obesity Biotech Debut Since Metsera

Clinical-stage Kailera aims to raise up to $533M on Nasdaq (ticker: KLRA), backed by four GLP-1-based candidates including a once-weekly injectable in Phase 3. The first obesity biotech IPO since Pfizer acquired Metsera for $10B signals renewed investor appetite for the $150B weight-loss market.

Apr 14, 2026 · 5 min read

CLINICAL SIGNAL

GLP-1 Agonists Enter Neuroprotection Era: Six Parkinson's Trials and Counting

A systematic review finds six published trials of GLP-1 therapies in Parkinson's disease, with lixisenatide's LIXIPARK trial showing superiority over placebo on motor endpoints. The data fuels a growing hypothesis that incretin-based drugs may slow neurodegeneration — not just metabolic disease.

Apr 13, 2026 · 6 min read

DEEP DIVE

Lilly's Oral GLP-1 and Triple Agonist Named Drugs to Watch for 2026

Clarivate highlights orforglipron (oral GLP-1) and retatrutide (GLP-1/GIP/glucagon triple agonist) as defining candidates in an obesity market projected to reach $150B by 2035. The peptide revolution accelerates.

Apr 13, 2026 · 8 min read

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