biotech.today

Details

  • Modalities: antibody-drug conjugates, small molecules, antibodies
  • Therapeutic areas: oncology, cardiovascular, rare diseases
  • Key targets: HER2, HER3, TROP2, B7-H3, CDH6
  • Indications: HER2+ breast cancer, HER2-low breast cancer, non-small cell lung cancer, colorectal cancer
  • Funding: N/A (public, Tokyo Stock Exchange: 4568, ~¥1.6T revenue FY2024)

Partners & investors

  • Public (TSE: 4568, OTC: DSNKY)· Investor
  • AstraZeneca (ADC co-development partner)· Investor

Key considerations

  • AI tools in use: DXd-ADC proprietary linker-payload platform, Computational antibody engineering, AI-assisted clinical trial optimization
  • DXd platform enables rapid generation of new ADC candidates with optimized drug-antibody ratios
  • Partnership with AstraZeneca (co-development of Enhertu and 3 other ADCs)
  • Five ADC launches planned in 2026 — unprecedented for the modality

Pipeline

  • Phase 34
  • Approved1
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Source: Company website, SEC / Companies House filings, press releases, Crunchbase · biotech.today analysis (Apr 2026)

Key people

Hiroyuki Okuzawa

CEO & Representative Director

oncology strategypharmaceutical commercializationADC development

Ken Keller

President, US Operations

oncology commercial launchmarket accessUS operations
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